pentobarbital will reduce the level or outcome of naloxegol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with powerful CYP3A4 inducers is just not encouraged pentobarbital will decrease the extent or influence of abiraterone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Kee